Frederick Eberson was born in New York, NY on February 10, 1892. He received degrees from College of the City of New York (B.S., 1912), Iowa State College (M.S., 1915), Columbia University College of Physicians and Surgeons (M.A., 1916, Ph.D., 1918) and the University of Minnesota School of Medicine (M.B., M.D., 1924). Prior to receiving his degree at Iowa State College, he served as an instructor in bacteriology. In 1916-1917 he served as a research bacteriologist in charge of the department of research bacteriology and pathology for the Northern Manchurian Plague Prevention Service in China. During service with the U. S. Army (1917-1919), he was assistant pathologist and bacteriologist at the Rockefeller Institute. From 1919-1921 he was an associate in dermatology and was in charge of the syphilis research laboratory at Washington University Medical School in St. Louis; a similar appointment at the Mayo Clinic occupied Dr. Eberson during 1922-1923.

Dr. Eberson came to the University of California School of Medicine as a resident and instructor in medicine (1924-1926), and rose to become an assistant professor (1926-1933); during this period he also served as a physician at the University Hospital and chest clinic (1924-1933) and an epidemiologist at this institution (1926-1931). He was physician-in-chief of the children's tuberculosis department at the University's San Francisco hospital (1927-1928) and was director of the clinical research laboratories and chief epidemiologist at Mt. Zion Hospital in San Francisco from 1929-1932. From 1934-1938 he served on the bureau of communicable diseases of the San Francisco Department of Public Health, and from 1938-1940 was a pathologist and chief of laboratory services at the U.S. Veterans Administration Facility.

During the early part of World War II (1940-1942) Dr. Eberson was at Gallinger Hospital in Washington, DC as pathologist and director of laboratories; from 1942-1952 he was pathologist and chief of laboratory services for the Veterans Administration Hospitals. Following an associate professorship in pathology and bacteriology at the Tennessee College of Medicine (1952-1954) and two years as the tri-county health director for the Kentucky State Department of Health (1954-1956), Dr. Eberson went to Western Kentucky State College as an associate professor of bacteriology and preventive medicine and the director of health and clinical services (1956-1962; emeritus professor, 1962-1970). He was associate clinical professor of community medicine at the University of Kentucky's medical center from 1964-1967, and clinical professor from 1967 until his retirement in 1970.